INTESTINAL LOCALIZATION
نویسندگان
چکیده
منابع مشابه
mRNA localization in polarized intestinal epithelial cells.
An important feature of enterocyte maturation is the asymmetrical distribution of cellular functions including protein localization. mRNA sorting is one mechanism for establishment and maintenance of this process in other systems, and we have previously demonstrated differential localization of mRNAs in human enterocytes. To study regulation of mRNA sorting, we established a model in polarized ...
متن کاملLocalization of human intestinal defensin 5 in Paneth cell granules.
Antibiotic peptides of higher animals include the defensins, first discovered in phagocytic cells but recently also found to be produced by epithelial cells. We biosynthesized recombinant human intestinal defensin 5 (rHD-5) using the baculovirus-insect cell expression system. Since insect cells process defensin incompletely and secrete the precursor proHD-5, we substituted a methionine for an a...
متن کاملIntracellular localization of CD14 protein in intestinal macrophages.
BACKGROUND Our research is focused on intestinal macrophages, which are believed to contribute to the maintenance of intestinal homeostasis. In addition, intestinal macrophages are unique in that there is an impairment of expression of tumor necrosis factor (TNF) from lipopolysaccharide (LPS). This characteristic can be attributed to the lack or poor level of expression of toll-like receptor 4 ...
متن کاملStudies on the Ultrastructural Localization of Intestinal Disaccharidases
It is now firmly established that disaccharidases are an intrinsic part of the mammalian intestinal (1) and renal (2) brush border. Isolated brush borders of hamster and rabbit intestine (3-6) are studded with knobs (65 A in diameter) or doughnut-shaped particles (45-110 A in diameter) respectively, when viewed as negatively stained preparations . Isolated brush borders of rabbit kidney do not ...
متن کاملThe localization of guanylate cyclase in rat small intestinal epithelium.
The distribution of guanylate cyclase activity among particulate and soluble fractions of broken cell preparations is strongly tissue-dependent. In scrapings from rat small intestinal epithelium virtually all activity has been found to be particulate [ 1,2] . Mucosal scrapings consist of a heterogeneous population of absorptive villous cells, proliferative and differentiating crypt cells and fr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American Medical Association
سال: 1909
ISSN: 0002-9955
DOI: 10.1001/jama.1909.25420400005001b